Posted on Thu, Sep 08, 2011
Prenatal Docosahexaenoic Acid Supplementation and Infant Morbidity: Randomized Controlled Trial
Pediatrics, 09/08/2011

Imhoff–Kunsch B et al. – Docosahexaenoic acid (DHA) supplementation during pregnancy decreased the occurrence of colds in children at 1 month and influenced illness symptom duration at 1, 3, and 6 months.
Methods
- In a double-blind randomized controlled trial conducted in Mexico, pregnant women received daily supplementation with 400 mg of DHA or placebo from 18 to 22 weeks' gestation through parturition.
- In infants aged 1, 3, and 6 months, caregivers reported the occurrence of common illness symptoms in the preceding 15 days.
Results
- Data were available at 1, 3, and 6 months for 849, 834, and 834 infants, respectively.
- The occurrence of specific illness symptoms did not differ between groups; however, the occurrence of a combined measure of cold symptoms was lower in the DHA group at 1 month. At 1 month, the DHA group experienced 26%, 15%, and 30% shorter duration of cough, phlegm, and wheezing, respectively, but 22% longer duration of ...read more
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Posted on Tue, Jun 07, 2011
Pediatric Radiology, 06/07/2011
Kim HY et al. – SPECT/CT precisely localizes neck iodine uptake. In small numbers of patients, treatment is affected. SPECT/CT should be used when available in thyroid carcinoma patients.
Methods
- 20 SPECT/CT and planar studies were reviewed in 13 children with papillary thyroid carcinoma after total thyroidectomy.
- Seven studies used I–123 and 13 used I–131, after elevating TSH by T4 deprivation or intramuscular thyrotropin alfa.
- Eight children had one study and five children had two to four studies.
- Studies were performed at initial post–total thyroidectomy evaluation, follow–up and after I–131 treatment doses.
- SPECT/CT was performed with a diagnostic–quality CT unit in 13 studies and a localization–only CT unit in 7.
- Stimulated thyroglobulin was measured (except in 2 cases with anti–thyroglobulin antibodies).
Results
- In 13 studies, neck activity was present but poorly localized on planar imaging; all foci of uptake were precisely localized by SPECT/CT. Two additional foci of neck uptake were found on SPECT/CT.
- SPECT/CT differentiated high neck uptake from ...read more
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Posted on Mon, Apr 25, 2011
Depression and Anxiety, 04/25/2011
Van Oort FVA et al. - Several child, family, and peer factors measured in preadolescence were risk indicators of high levels of anxiety symptoms throughout adolescence. Some factors (such as rejective parenting) were vulnerability indicators for anxiety in early adolescence only, whereas other factors (such as peer victimization) were indicators of long-term elevated anxiety levels.
Methods
- Anxiety symptoms were assessed in a community sample of 2,220 boys and girls at three time-points across a 5-year interval.
- Risk indicators were measured at baseline and include indicators from the child, family, and peer domain.
- Associations with anxiety were measured with multilevel growth curve analyses.
Posted on Fri, Apr 15, 2011
Pediatric Pulmonology, 04/15/2011
Barben J et al. - Mannitol dry powder (MDP) challenge test is feasible in children and is a suitable alternative for bronchial challenge testing in childhood.
Methods
- Children aged 6–16 years, referred to two respiratory outpatient clinics for possible asthma diagnosis, underwent standardized exercise testing followed within a week by an MDP challenge.
- Agreement between the two challenge tests using Cohen's kappa and receiving operating characteristic (ROC) curves was compared.
Posted on Wed, Mar 30, 2011
Journal of Pediatric Hematology/Oncology, 03/30/2011
El–Matary W et al. – In a case–control study, medical records of all children (below 18 y of age) who were diagnosed with any malignancy between January 1988 and December 2008 were reviewed. Children who developed typhlitis during the course of their malignancy were identified. Age and sex–matched ...read more
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Posted on Tue, Mar 15, 2011
InnovAiT, 03/14/2011
Mason K et al. – The need for teenage contraceptive services is highlighted by the relatively poor sexual health of adolescents in the UK. Young people are currently disproportionately affected by sexually transmitted diseases, and although the teenage pregnancy rate is falling, it is still not at the level experienced by ...read more
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Posted on Tue, Mar 08, 2011
Acta Pediatrica, 03/08/2011
Mazur L et al. – Children with spina bifida have a significantly higher prevalence of hypertension than children in the general population. Age, gender, and height based norms are important for the early identification and treatment of hypertension in children.
Methods
- All patients (n=123) seen in the Spina Bifida Clinic at Shriners Hospital in Houston, Texas were reviewed for age, gender, ethnicity, type and level of neural tube defect, height, weight, and blood pressure.
- Hypertension was defined as a systolic blood pressure or diastolic blood pressure >95th percentile for age, gender, and height on >3 occasions.
- Data from the National Health and Nutrition Examination Survey and from a Houston–based study were used for comparison.
Posted on Thu, Jan 27, 2011
Formulary , 01/27/2011 Free full text Clinical Article
Researchers from the Cincinnati Children's Hospital Medical Center have demonstrated that the tumor necrosis factor (TNF)–alpha inhibitor etanercept is associated with significant increases in height, weight, and body mass index (BMI) in children with juvenile idiopathic arthritis (JIA), according to a study recently...read more
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Posted on Wed, Jan 19, 2011
Pediatric Pulmonology, 01/19/2011
Soong WJ et al. – A 9–year–old boy who developed a life–threatening anaphylaxis reaction of the airway and subsequent dyspnea and circulation collapse because of instilled the topical lidocaine into the airway within 2min before performing flexible bronchoscopy (FB). FB revealed swollen airway mucosa and extensive foamy secretion that severely compromised the ventilation lumen. Rapid detection with FB and immediate resuscitation, including prompt administration of epinephrine, volume expander, and ...read more
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Posted on Fri, Jan 14, 2011
Current Opinion in Lipidology, 01/14/2011
Reinehr T et al. – A new promising prevention approach is to change the environment. Therapy of choice in already obese children is lifestyle intervention. Again, including their parents is crucial for success. However, this kind of intervention is only suitable for families motivated to change their lifestyle habits. Especially in extremely obese adolescents, additional therapeutic approaches such as drugs and bariatric surgery have to be considered. Even if of knowledge of childhood obesity improves every year, many...read more
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