As published in the Journal of Clinical Oncology, patients with colorectal cancer who underwent colonoscopy prior to diagnosis had a lower mortality rate than patients who did not. The mortality rate was also lower in patients with distal vs. proximal lesions, and patients who underwent colonoscopy performed by a gastroenterologist.
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As published in Cancer
, NSAIDs decrease the risk of squamous cell carcinoma (SCC; IRR=0.85) and malignant melanoma (MM; IRR=0.87). Aspirin, non-selective NSAIDs, and selective COX-2 inhibitor useanalyzed in all incident cases of SCC (n=1974), basal cell carcinoma (n=13316), and MM (n=3242) recorded in northern Denmark between 1991 and 2009. Long-term (>
7 years) and high intensity use (> 25% prescription coverage during entire interval of use) were particularly protective.
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As published in the Annals of Internal Medicine
, a meta-analysis of the extant literature (1966-2011) suggests that first-degree relatives with adenomatous polyps impart an increased risk of colorectal cancer (RR = 2.27-4.36).
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As published in The Lancet
, an analysis of five large randomized studies conducted in the UK has shown that low-dose aspirin (>
75 mg/d) for vascular disease prophylaxis decreases the risk of distant metastases. The analysis included 17,285 patients with 987 incident solid cancers during a mean follow-up of 6.5 y. The HRs for distant metastases in all cancers, adenocarcinomas, and other solid cancers were 0.64, 0.54, and 0.82, respectively. Further, the HR for cancer-related death in patients with adenocarcinomas was 0.50.
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Different Characteristics of Thymomas With and Without Myasthenia Gravis
Annals of Surgical Oncology, 09/14/2011
Yu L et al. – Myasthenia gravis (MG) seldom occurs in types A and C thymoma. MG of some thymoma patients was not caused by thymoma, but by the paraneoplastic thymus. The prognosis of thymomas with MG is similar to that without MG. The main cause of death is myasthenia crisis for thymoma patients with MG and stage IV and/or type C for thymoma patients without MG...read more
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