Risk Factors and Preventive Interventions for Alzheimer Disease: State of the Science
Posted on Wed, May 11, 2011
Archives of Neurology, 05/11/2011
Daviglus ML et al. – Currently, insufficient evidence exists to draw firm conclusions on the association of any modifiable factors with risk of Alzheimer disease(AD).
Methods
- Study inclusion criteria for the evidence report were participants aged 50 years and older from general populations in developed countries.
- Minimum sample sizes of 300 for cohort studies and 50 for randomized controlled trials.
- At least 2 years between exposure and outcome assessment; and use of well–accepted diagnostic criteria for AD.
- Included studies were evaluated for eligibility and data were ed.
- Quality of overall evidence for each factor was summarized as low, moderate, or high.
