Long-term effects of weight-reducing diets in hypertensive patients
Posted on Mon, Sep 12, 2011
Long-term effects of weight-reducing diets in hypertensive patients
Cochrane Reviews, 09/12/2011 Clinical Article
Siebenhofer A et al. - In patients with primary hypertension, weight loss diets reduced body weight and blood pressure, however the magnitude of the effects are uncertain as a result of the small number of patients and studies that could be included in the analyses. It is not known whether weight loss reduces mortality and morbidity. No useful information on adverse effects was reported in the relevant trials.
Methods
- Studies were obtained from computerised searches of Ovid MEDLINE, EMBASE, CENTRAL and from searches in reference lists and systematic reviews.
- Randomised controlled trials (RCT) in adult hypertensive patients were included if they had a study duration of at least 24 weeks and compared weight reducing dietary interventions to no dietary intervention in adult patients with primary hypertension.
- Two authors independently assessed risk of bias and extracted data.
- Studies were pooled using fixed-effect meta-analysis.
- In case of moderate or larger heterogeneity as measured by Higgins I2, a random effects model was used...read more
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