Posted on Sun, Mar 18, 2012
Pro-carboxypeptidase A (PCPA) levels were determined in 10 and 16 patients with early and late adenocarcinoma of the head of the pancreas, respectively. The upper limit of normal of 2.35 u/L for PCPA was exceeded in 90% and 56% of patients with early- and late-stage pancreatic cancer, respectively. PCPA was shown to have a sensitivity of 94% in the detection of early-stage pancreatic cancer.